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June 12, 2025

A Guide to Laboratory Safety Practices That Save Lives

Laboratories are hubs of discovery, but they’re also packed with risks. Following proper laboratory safety practices isn’t just about rules; it’s the non-negotiable divide between a breakthrough and a bad accident. From mystery chemicals to complex gear, this guide is your plan for smart laboratory safety practices that save lives.

Proactive Hazard Identification and Control

The Hierarchy of Controls is a valuable framework that guides us in selecting the most effective methods to mitigate risks. It prioritizes controls from most effective to least effective:

  1. Elimination: Remove the hazard completely.
  2. Substitution: Replace the hazard with a less hazardous alternative.
  3. Engineering Controls: Isolate the hazard through fume hoods, safety guards, or ventilation systems.
  4. Administrative Controls: Implement training, standard operating procedures, and signage.
  5. Personal Protective Equipment (PPE): Use gloves, lab coats, safety glasses, and respirators as a last resort.

PPE should always be a last line of defense, not a primary control measure.

Common Laboratory Hazards

Identify hazards in your lab and consult Safety Data Sheets (SDSs) for appropriate precautions.

Equipment Maintenance and Safety

Regular inspections, cleaning, and calibration prevent malfunctions and reduce accident risks. Always follow manufacturer guidelines and report damaged or faulty equipment immediately.

Professionalism and Laboratory Conduct

Emergency Preparedness in Laboratories

Even with precautions, emergencies can still happen. A well-defined emergency response plan ensures personnel safety and minimizes damage. The plan should include:

Key Resources for Emergency Response

Laboratory safety requires continuous commitment. By implementing safe work practices, controlling hazards, maintaining equipment, and preparing for emergencies, you can create a safer lab environment for all.


Frequently Asked Questions About Laboratory Safety

What is the most important laboratory safety practice?

The single most important practice is situational awareness. This means always knowing the hazards in your experiment, wearing the correct PPE, knowing the location of emergency equipment (like the eyewash station and safety shower), and never working alone on a hazardous procedure.

What is the Hierarchy of Controls in a lab?

It’s a 5-step model to pick the *most* effective safety solution. The best option is Elimination (remove the hazard), followed by Substitution (use a safer chemical), Engineering Controls (use a fume hood), Administrative Controls (training and procedures), and finally, PPE (your last line of defense).

What should be in a lab’s Chemical Hygiene Plan?

An OSHA-required Chemical Hygiene Plan must include: Standard Operating Procedures (SOPs) for hazardous chemicals, criteria for selecting and using PPE, measures to ensure equipment (like fume hoods) is working, and details on employee training and medical consultation.


Expand Your Knowledge

Expand your knowledge with our Laboratory Safety: Safe Work Practices Training Course. For a deeper dive into regulations and best practices, consider enrolling in our specialized Laboratory Safety Certification Program.


References

Occupational Safety and Health Administration (OSHA) – Laboratory Standard Occupational Safety and Health Administration (OSHA) – Hazard Communication Standard Centers for Disease Control and Prevention (CDC) – Biosafety in Microbiological and Biomedical Laboratories

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