June 12, 2025
A Guide to Laboratory Safety Practices That Save Lives

June 12, 2025

Laboratories are hubs of discovery, but they’re also packed with risks. Following proper laboratory safety practices isn’t just about rules; it’s the non-negotiable divide between a breakthrough and a bad accident. From mystery chemicals to complex gear, this guide is your plan for smart laboratory safety practices that save lives.
The Hierarchy of Controls is a valuable framework that guides us in selecting the most effective methods to mitigate risks. It prioritizes controls from most effective to least effective:
PPE should always be a last line of defense, not a primary control measure.
Identify hazards in your lab and consult Safety Data Sheets (SDSs) for appropriate precautions.
Regular inspections, cleaning, and calibration prevent malfunctions and reduce accident risks. Always follow manufacturer guidelines and report damaged or faulty equipment immediately.
Even with precautions, emergencies can still happen. A well-defined emergency response plan ensures personnel safety and minimizes damage. The plan should include:
Laboratory safety requires continuous commitment. By implementing safe work practices, controlling hazards, maintaining equipment, and preparing for emergencies, you can create a safer lab environment for all.
The single most important practice is situational awareness. This means always knowing the hazards in your experiment, wearing the correct PPE, knowing the location of emergency equipment (like the eyewash station and safety shower), and never working alone on a hazardous procedure.
It’s a 5-step model to pick the *most* effective safety solution. The best option is Elimination (remove the hazard), followed by Substitution (use a safer chemical), Engineering Controls (use a fume hood), Administrative Controls (training and procedures), and finally, PPE (your last line of defense).
An OSHA-required Chemical Hygiene Plan must include: Standard Operating Procedures (SOPs) for hazardous chemicals, criteria for selecting and using PPE, measures to ensure equipment (like fume hoods) is working, and details on employee training and medical consultation.
Expand your knowledge with our Laboratory Safety: Safe Work Practices Training Course. For a deeper dive into regulations and best practices, consider enrolling in our specialized Laboratory Safety Certification Program.
Occupational Safety and Health Administration (OSHA) – Laboratory Standard Occupational Safety and Health Administration (OSHA) – Hazard Communication Standard Centers for Disease Control and Prevention (CDC) – Biosafety in Microbiological and Biomedical Laboratories